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SCHMERZ
Hannover 26. - 29. März 2012


Montag 26. März 2012

 

09:00-10:00 Übersichtsvortrag

 

10:00-10:30 Epidemiologie des Schmerzes

 

 

Der chronische Schmerz - Epidemiologie und Versorgung in Deutschland
Zimmermann, M.
Orthopde 2004 33:508–514

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Epidemiology of Neuropathic Pain and its Impact of Quality of Life
Smith BH, Torrance N.
Curr Pain Headache Rep. DOI 10.1007/s11916-012-0256-0

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Epidemiologie und Kosten chronischer Schmerzen - Spezifische und unspezifische Rückenschmerzen
Göbel H.
Schmerz 2001 15:92–98

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11:00-12:30 Vortragsblock

 

 

Kortikale Repräsentation des Schmerzsinns

 

 

Human brain mechanisms of pain perception and regulation in health and disease
Apkarian AV, Bushnell MC, Treede RD, Zubieta JK.
Eur J Pain. 2005 Aug;9(4):463-84. Epub 2005 Jan 21.

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Significance of the insula for the evolution of human awareness of feelings from the body
Craig AD
Ann. N.Y. Acad. Sci. 1225 (2011) 72–82

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Philosophie und Ethik

 

 

Ethik-Charta der DGSS
ISBN 978-3-9806595-4-3

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Transduktionsmechanismen der Nozizeption

 

 

Molecular mechanisms of nociception
Julius D, Basbaum AI
Nature Vol 413 13 September 2001 203-210

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Pharmacology of Vanilloid Transient Receptor Potential Cation Channels
Vriens J, Appendino G, Nilius B.
Mol Pharmacol 75:1262–1279, 2009

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14:30-16:00 Vortragsblock

 

 

Deszendierende Schmerzmodulation

 

 

Preclinical and Early Clinical Investigations Related to Monoaminergic Pain Modulation
Bannister K, Bee LA, Dickenson AH.
The Journal of the American Society for Experimental NeuroTherapeutics Vol. 6, 703–712, October 2009

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Schmerz kontra Schmerz - Das Prinzip der DNIC
Sprenger C, May A, Büchel C.
Schmerz 2010 · 24:569–574

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Plastizität des nozizeptiven Systems

 

 

Central mechanisms of pathological pain
Kuner R.
Nature Medicine Vol 16 No 11 November 2010 1258-1266

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Common pattern of plasticity contributing to nociceptive sensitization in mammals and Aplysia
Woolf CJ, Walters ET.
TINS Vol 14 No 2 1991 74-78

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Schmerz und Schlaf incl. RLS

 

 

Diurnal time course of heat pain perception in healthy humans
Bachmann CG, Nitsche MA, Pfingsten M et al.
Neuroscience Letters 489 (2011) 122–125

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Sleep deprivation and pain perception
Lautenbacher S, Kundermann B, Krieg JC.
Sleep Med Rev. 2006 Oct;10(5):357-69. Epub 2006 Jan 4

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The Effects of Sleep Deprivation on Pain Inhibition and Spontaneous Pain in Women
Smith M; Edwards R, McCann U et al.
Sleep 2007;30(4):494-505

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Static mechanical hyperalgesia without dynamic tactile allodynia in patients with restless legs syndrome
Stiasny-Kolster K, Magerl W, Oertel WH et al.
Brain (2004), 127, 773782

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Thermal hypoaesthesia differentiates secondary restless legs syndrome associated with small fibre neuropathy from primary restless legs syndrome
Bachmann CG, Rolke R, Scheidt U et al.
Brain 2010: 133; 762–770

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Sleep restriction attenuates amplitudes and attentional modulation of pain-related evoked potentials, but augments pain ratings in healthy volunteers
Tiede W, Magerl W, Baumgärtner U et al.
PAIN 148 (2010) 36–42

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16:30-18:00 Vortragsblock

 

Dienstag 27. März 2012

 

09:00-09:30 Grundlagen

 

 

Pharmakotherapie des Schmerzes
Teepker M.
Vortragsfolien

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Schmerztherapie und Symptomkontrolle in der Palliativmedizin
Klaschik E.
Kap. 4, 203-307

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09:30-10:00 Kopfschmerzen Klassifikation

 

 

Klassifikation von Kopfschmerzen
Heinze A, Heinze-Kuhn K, Göbel H.
Schmerz 2007 E 21:263–274

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10:00-10:10 Kopfschmerzen und Hormone

 

 

Migräne und Hormone: Was ist gesichert?
Bingel U.
Schmerz 2008 · [Suppl 1] 22:31–36

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Incidence of migraine relative to menstrual cycle phases of rising and falling estrogen
MacGregor EA, Frith A, Ellis J et al.
Neurology 2006;67;2154-2158

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The Effects of Oral Contraceptives on Detection and Pain Thresholds As Well As Headache Intensity During Menstrual Cycle in Migraine
Teepker M, Peters M, Kundermann B.
Headache 2011;51:92-104

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10:10-10:30 Sekundäre Kopfschmerzen

 

 

Kopfschmerz als Warnsymptom: Red Flags
Sternberg S, Bingel U, May A.
Akt Neurol 2006; 33: 107118

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Diagnostik und apparative Zusatzuntersuchungen bei Kopfschmerzen
Leitlinie der Deutschen Gesellschaft für Neurologie (DGN) 2008

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11:00-12:30 Vortragsblock Primäre Kopfschmerzen

 

 

Chronische Spannungskopfschmerzen

 

 

Myofascial trigger points and sensitization: an updated pain model for tension-type headache
Fernndez-de-las-Peas C, Cuadrado ML, Arendt-Nielsen L et al.
Cephalalgia 2007; 27:383–393

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Impairment of pain inhibition in chronic tension-type headache
Pielsticker A, Haag G, Zaudig M et al.
Pain 118 (2005) 215–223

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Clusterkopfschmerz

 

 

Cluster headache: pathogenesis, diagnosis, and management
May A.
Lancet 2005; 366: 843–55

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Cluster Headache: Diagnosis and Treatment
Halker R, Vargas B, Dodick DW.
Semin Neurol 2010;30:175–185

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Diffusion Tensor Imaging in Episodic Cluster Headache
Teepker M, Menzler K, Belke M et al.
Headache 2012;52:274-282

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EFNS guidelines on the treatment of cluster headache and other trigeminalautonomic cephalalgias
May A, Leone M, Afra J et al.
European Journal of Neurology 2006, 13: 1066–1077

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Migräne

 

 

Current practice and future directions in the prevention and acute management of migraine
Goadsby PJ, Sprenger T.
Lancet Neurol 2010; 9: 285–98

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Pathophysiology of Migraine
Cutrer FM.
Semin Neurol 2010;30:120–130

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14:30-16:00 Vortragsblock Andere Kopfschmerzen

 

 

Chronische peroxismale Hemicranie - Atypische Gesichtsschmerzen

 

 

Atypical facial pain: clinical considerations and differential diagnosis
Agostoni E, Frigerio R, Santoro P.
Neurol Sci (2005) 26:S71–S74

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EFNS guidelines on the treatment of cluster headache and other trigeminalautonomic cephalalgias
May A, Leone M, Afra J et al.
European Journal of Neurology 2006, 13: 1066–1077

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Facial Pain
Graff-Radford SB.
The Neurologist Vol 15 No 4 July 2009 171-177

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Kopfschmerzattacken und autonome Symptome
May A.
Schmerz 2004 ·E 18:370–377

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Trigeminal Autonomic Cephalalgias: Paroxysmal Hemicrania, SUNCT/SUNA, and Hemicrania Continua
Goadsby PJ, Cittadini E, Cohen AS.
Semin Neurol 2010;30:186–191

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Kopfschmerzen bei Medikamentengebrauch

 

 

Kopfschmerz bei Medikamentenübergebrauch
Leitlinie der Deutschen Gesellschaft für Neurologie (DGN) 2008

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Prevention of medication overuse in patients with migraine
Fritsche G, Frettlöh J, Hüppe M et al.
PAIN 151 (2010) 404–413

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Trigeminusneuralgie

 

 

Pharmacological versus microvascular decompression approaches for the treatment of trigeminal neuralgia: clinical outcomes and direct costs
Lemos L, Alegria C, Oliveira J et al.
Journal of Pain Research 2011:4 233–244

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Trigeminusneuralgie
Leitlinie der Deutschen Gesellschaft für Neurologie (DGN) 2008

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16:30-18:00 Bildgebung

 

Mittwoch 28. März 2012

 

09:00-09:30 CRRS

 

 

Clinical features and pathophysiology of complex regional pain syndrome
Marinus J, Moseley GL, Birklein F et al.
Lancet Neurol 2011; 10: 637–48

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Diagnostik und Therapie komplexer regionaler Schmerzsyndrome (CRPS)
Leitlinie der Deutschen Gesellschaft für Neurologie (DGN) 2008

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09:30-10:00 Vortragsblock

 

 

Radikulopathie

 

 

Back Surgery — Who Needs It?
Deyo RA.
N Engl J Med 356;22 may 31, 2007 2239-2243

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Surgery versus Prolonged Conservative Treatment for Sciatica
Peul WC, van Houwelingen HC, van den Hout WB et al.
N Engl J Med 2007;356:2245-56

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Schmerzen bei Borreliose

 

10:00-10:30 Tumorschmerz + Vaskul

 

 

Central post-stroke pain: clinical characteristics, pathophysiology, and management
Klit H, Finnerup NB, Jensen TS.
Lancet Neurol 2009; 8: 857–68

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Treatment of cancer pain
Portenoy RK.
Lancet 2011; 377: 2236–47

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11:00-11:30 Neuropathischer Schmerz - Einführung

 

 

Diagnostik neuropathischer Schmerzen
Leitlinine der Deutschen Gesellschaft für Neurologie (DGN) 2008

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11:30-12:30 Neuropathische und andere Schmerzen

 

 

Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment
Baron R, Binder A, Wasner G.
Lancet Neurol 2010; 9: 807–19

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Myopathie

 

 

Diagnostik von Myopathien
Leitlinine der Deutschen Gesellschaft für Neurologie (DGN) 2008

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Myositiden
Leitlinine der Deutschen Gesellschaft für Neurologie (DGN) 2008

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Rituximab for the Treatment of Juvenile Dermatomyositis
Cooper MA, Willingham DL, Brown DE et al.
Arthritis & Rheumatism Vol 56 No 9 September 2007 3107–3111

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Polyneuropathie

 

 

Diagnostik bei Polyneuropathien
Leitlinine der Deutschen Gesellschaft für Neurologie (DGN) 2008

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Peripheral neuropathy
England JD, Asbur AK.
Lancet 2004; 363: 2151–61

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14:30-16:00 Therapieverfahren

 

 

Medikamentöse Therapie neuropatischer Schmerzen

 

 

Efficacy of pregabalin in neuropathic pain evaluated in a 12-week, randomised, double-blind, multicentre, placebo-controlled trial of flexible- and fixed-dose regimen
Freynhagen R, Strojek K, Griesing T et al.
Pain 115 (2005) 254–263

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Chronic Neuropathic Pain - Mechanisms, Diagnosis, and Treatment
Harden RN.
The Neurologist 2005;11: 111–122

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Therapie neuropathischer Schmerzen
Leitlinie der Deutschen Gesellschaft für Neurologie (DGN) 2008

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Stimulationsverfahren

 

 

Spinal cord stimulation in failed back surgery syndrome
De La Porte C, Van de Kelft E.
Pain. 1993 Jan;52(1):55-61

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Spinal Cord Stimulation for Patients with Failed Back Surgery Syndrome: A Systematic Review
Frey ME, Manchikanti L, Benyamin RM et al.
Pain Physician 2009; 12:379-397

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Predictive Value of rTMS in the Identification of Responders to Epidural Motor Cortex Stimulation Therapy for Pain
Lefaucheur J-P, Menard-Lefaucheur I, Goujon C et al.
The Journal of Pain Vol 12 No 10 (October) 2011 1102-1111

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Long-term maintenance of the analgesic effects of transcranial magnetic stimulation in fibromyalgia
Mhalla A, Baudic S, Ciampi de Andrade D et al.
PAIN 152 (2011) 1478–1485

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16:30-17:00 Schmerz und Demenz

 

 

Influence of dementia on multiple components of pain
Kunz M, Mylius V, Scharmann S et al.
European Journal of Pain 13 (2009) 317–325

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Pain sensitivity and fMRI pain-related brain activity in Alzheimer’s disease
Cole LJ, Farrell MJ, Duff EP et al.
Brain (2006) 129, 2957–2965

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17:00-17:30 Fibromyalgie

 

17:30-18:00 Schmerzforschung

 

Donnerstag 29. März 2012

 

09:00-09:30 Schmerzforschung in der Psychologie

 

09:30-10:00 Erfassung und Messung des Schmerzes

 

10:00-10:30 Erfassung von TherapieeffektenSchmerzes

 

11:00-11:30 Schmerz und Depression

 

 

Influence of dementia on multiple components of pain
Kunz M, Mylius V, Scharmann S et al.
European Journal of Pain 13 (2009) 317–325

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Pain sensitivity and fMRI pain-related brain activity in Alzheimer’s disease
Cole LJ, Farrell MJ, Duff EP et al.
Brain (2006) 129, 2957–2965

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11:30-12:00 Rückenschmerzen

 

 

Behavioural treatment for chronic low-back pain (Review)
Henschke N, Ostelo RWJG, van Tulder MW et al.
The Cochrane Library 2011 Issue 2

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The role of operant conditioning in chronic pain: an experimental investigation
Flor H, Knost B, Birbaumer N.
Pain 95 (2002) 111–118

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Auf den Spuren der Rumpfmuskeln
Sprotta H, Pulkovskia N, Manniona AF.
Schweiz Med Forum 2008;8(25):478–480

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12:00-12:30 Fibromyalgie II

 

 

Are psychological treatments effective for fibromyalgia pain?
Thieme K, Gracely RH.
Curr Rheumatol Rep. 2009 Dec;11(6):443-50

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Functional Magnetic Resonance Imaging Evidence of Augmented Pain Processing in Fibromyalgia
Gracely RH, Petzke F, Wolf JM et al.
Arthritis & Rheumatism Vol 46 No 5 May 2002 1333–1343

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14:30-15:00 Tiermodelle für die Schmerzforschung

 

15:00-15:30 CCI and SNL

 

 

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
Bennett GJ, Xie YK.
Pain. 1988 Apr;33(1):87-107

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An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat
Kim SH, Chung JM.
Pain. 1992 Sep;50(3):355-63

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15:30-16:30

 

 

Unmasking the tonic-aversive state in neuropathic pain
King T, Vera-Portocarrero L, Gutierrez T et al.
Nat. Neurosci. 12, 1364–1366 (2009); published online 27 September 2009; corrected after print 9 June 2010

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16:30-18:00

 

 

Ethical Guidelines for Investigations of Experimental Pain in Conscious Animals
International Association for the Study of Pain

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Lacosamide: A Review of Preclinical Properties
Beyreuther BK, Freitag J, Heers C et al.
CNS Drug Reviews Vol 13 No 1 21–42

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Lacosamide for neuropathic pain and fibromyalgia in adults (Review)
Hearn L, Derry S, Moore RA.
The Cochrane Library 2012 Issue 2

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Ziconotide: a review of its pharmacology and use in the treatment of pain
McGivern JG.
Neuropsychiatric Disease and Treatment 2007:3(1) 69–85

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Ziconotide for treatment of severe chronic pain
Schmidtko A, Lötsch J, Freynhagen R et al.
Lancet 2010; 375: 1569–77

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